Personalised medicine aims to provide medical treatment tailored even more to the individual precisely, maximising efficacy while reducing the chance of a detrimental reaction. According to articles released this month in Nature Reviews Microbiology the experts think that gut microbes, which influence both biochemistry and immune system of the host, could play a key role in modulating how medications can affect the body. As the community of microbes varies between individuals this may have important implications for the advancement of personalised treatments, and for drug discovery.WORK showcases future technology and innovations in deep learning softwareThe team possess summarised the scientific proof showing that gut microbes have a lot of interactions with the body, and that changes to their composition could have significant effects, both bad and good, on a person.Due to the amount of discomfort and pain, the rectal examination, where a finger can be inserted into the rectum to experience for abnormalities also to check for blood in the stool, is usually deferred. If the fissure is not seen and there is definitely doubt about the medical diagnosis, a flexible sigmoidoscopy could be considered, where the healthcare practitioner inserts a brief lighted tube into the anus to inspect the region. Usually, lidocaine ointment is used as an anesthetic to make the procedure less uncomfortable.