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This is a significant breakthrough as the MAP3K1 gene provides brand-new insights into regular testis development and significantly increases the number of DSD situations we can diagnose later on.’ The study, today in the American Journal of Individual Genetics published, was undertaken in collaboration with the Women’s and Children’s Hospital, Adelaide, New York University School of Medicine, MRC Mammalian Genetics Unit, UK, Centre Hospitalier Universitaire de Nantes, France.. Alteration in gene causes male embryos to build up as females Scientists can see that the alteration of an individual gene might lead to some man embryos to develop while females.